A Pictogram of Nipah Virus Infection and Treatment

Kumar: A Pictogram of Nipah Virus Infection and Treatment

Authors

Nipah virus (NIV) belongs to Henipavirus genus in the family of paramaxoviridae, which are negative sense single stranded RNA virus.1 Nipah virus is naturally harboured in fruit eating pteropid bats and is reported to cause neurological and respiratory disease in pigs, horses and humans. NIV infection is prevalent in the south Asian region. NIV infection is associated with high fatality rate, which is reported to be 40-75%. Below is a pictogram (Figure 1) of NIV infection, symptoms, pathology and currently known treatment options,2-4 which will be useful to patients as well as healthcare professionals.

Figure 1

A pictogram of Nipah virus infection and treatment.

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REFERENCES

1. 

Ang BSP, Lim TCC, Wang L, authors. Nipah Virus Infection. J Clin Microbiol. 2018

2. 

Lo MK, author. et al. Susceptibility of paramyxoviruses and filoviruses to inhibition by 2’-monofluoro- and 2’-difluoro-4’-azidocytidine analogs. Antiviral Res. 2018;153:101–13

3. 

Dawes BE, author. et al. Favipiravir (T-705) protects against Nipah virus infection in the hamster model. Sci Rep. 2018;8:7604

4. 

Geisbert TW, author. et al. Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody. Sci Transl Med. 2014;6:242ra82



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